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This KB describes the problem exactly and brings up a solution: https://support.microsoft.com/kb/2661910
But in a few sentences.
There are two ways to solve that problem:
- add a RegKey to all Clients
Windows Registry Editor Version 5.00
[HKEY_CLASSES_ROOT\MIME\Database\Content Type\application/vnd.ms-powerpoint.presentation.12]
"Extension"=".pptx" - Set the Browser File Handling setting within WebApplication settings to permissive instead of strict.
Here's a little more information to "Browser File Handling" (what is it)